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Publikationen unserer Mitarbeiter aus dem Bereich Immungenetik

Hirv K, Bloch K, Fischer M, Einsiedler B, Schrezenmeier H, Mytilineos J. Prediction of duration and success rate of unrelated hematopoietic stem cell donor searches based on the patient's HLA-DRB1 allele and DRB1-DQB1 haplotype frequencies. Bone Marrow Transplant (accepted for publication).

Hinrichs J, Figueiredo C, Hirv K, Mytilineos J, Blasczyk R, Horn PA, Eiz-Vesper B. Discrimination of HLA null and low expression alleles by cytokine-induced secretion of recombinant soluble HLA. Mol Immunol 2009 Feb 3; (Epub ahead of print). DOI: 10.1016/j.molimm.2008.12.011.

Hirv K, Pannicke U, Mytilineos J, Schwarz K. Disulfide bridge disruption in the ?2 domain of the HLA class I molecule leads to low expression of the corresponding antigen. Hum Immunol 2006;67:589-596.

Stachel DK, Leipold A, Kuhlen M, Gravou-Apostolatou C, Hirv K, Bader P, Niemeyer CM, Beck JD, Holter W. Simultaneos control of third-degree graft-versus-host disease and prevention of recurrence of juvenile myelomonocytic leukemia (JMML) with 6-mercaptopurine following fulminant JMML relapse early after KIR-mismatched bone marrow transplantation. J Pediatr Hematol Oncol 2005;27:672-674.

K. Hoelsch, I. Lenggeler, W. Pfannes, H. Knabe, H.-G. Klein, A. Wölpl. Routine HLA-B genotyping with PCR-sequence-specific oligonucleotides detects a B*52 variant (B*5206). Tissue Antigens. 65(5):488-92, 2005.

K. Witter, A. Wölpl, R. Zahn, H.-G. Klein, E.D. Albert. Sequence-based typing confirmed a novel B*40 allele, B*4046, which was identified through sequence-specific oligonucleotide hybridization routine typing. Tissue Antigens 63(4):378-81, 2004.

Eichler, H., Wölpl, A., Goldmann, S.F. Sample identification errors in cord blood banking. Tissue Antigens 57; 91-92, 2001
 
Eichler, H., Wölpl, A., Schwarz, K., Richter, E., Goldmann, S.F. Sample identification errors observed within a study for molecular cord blood HLA typing. Infusion Therapy and Transfusion Medicine 27: 16-18, 2000

Arndt, SO., Vogt, AB., Markovic-Plese, S., Martin, R., Moldenhauer, G., Wölpl, A., Sun, Y., Schadendorf, D., Hämmerling, GJ., Kropshofer, H.: Functional HLA-DM on the surface of B cells and immature dendritic cells. Embo Journal 19, 1241-1251, 2000

Elsner, H.-A., Wölpl, A., Goldmann, S. F., Blasczyk, R. Identification of the novel allele HLA-B* 1546 which belongs to the serological B72 type: implications for bone marrow transplantation Tissue Antigens 55; 83-85, 2000

Hirv K, Seyfarth M, Uibo R, Kull K, Salupere R, Latza U, Rink L. Polymorphisms in tumour necrosis factor and adhesion molecule genes in patients with inflammatory bowel disease: associations with HLA-DR and --DQ alleles and subclinical markers. Scand J Gastroenterol 1999;34:1025-1032.

Schwarz, K., Wölpl, A., Spegel, J., Mueller, C., Goldmann, S. F. Caucasian German Normal In: HLA 1998 (Editors: D.W. Gjertson & P.I. Terasaki) American Society for Histocompatibility and Immunogenetics Lenexa, Kansas, USA, 1998, S. 149
 
Eichler, H., Richter, E., Schwarz, K., Woelpl, A., Goldmann, S. F. Turkish Normal In: HLA 1998 (Editors: D.W. Gjertson & P.I. Terasaki) American Society for Histocompatibility and Immunogenetics Lenexa, Kansas, USA, 1998, S. 190-191
 
Eichler, H., Richter, E., Schwarz, K., Woelpl, A., Goldmann, S. F. Caucasian German Normal. In: HLA 1998 (Editors: D.W. Gjertson & P.I. Terasaki) American Society for Histocompatibility and Immunogenetics Lenexa, Kansas, USA, 1998, S. 150-151

Löffler, D., Welschof, M., Goldmann, S. F., Wölpl, A. Recognition of HLA-DR1/DRB1*0101 molecules presenting HLA-A2 derived peptides by a human recombinant antibody, Fab-5A1. European Journal of Immunogenetics 25, 339-347, 1998
 
Wölpl, A., Halden,T., Kalbacher, H., Neumeyer, H., Siemoneit, K., Goldmann, S. F., Eiermann, Th. Human monoclonal antibody with T-cell-like specifity recognizes MHC class I self-peptide presented by HLA-DR1 on activated cells. Tissue Antigens 51; 258-269 1998
 
Wagner, F., Simoneit, K., Wölpl, A., Flegel.: Humaner monoklonaler Antikörper gegen enzymbehandelte Erythrozyten. Beitr. Infusionsther. Transfusionsmed. Basel, Karger, 33, 40-42, 1996
 
Schreiner, Th., Prochnow-Calzia, H., Maccari, B., Erne, E., Kinzler, I., Wölpl, A., Wiesneth, M. Chimerism analysis after allogenic bone marrow transplantation with nonradioactive RFLP and PCR-AFLP using the same DNA. Journal of Immunological Methods, 196, 93-96, 1996
 
Wölpl, A., Toubert, A., Siemoneit, K., Eiermann, Th., Neumayer H., Goldmann, S. F. Characterization of two human IgM monoclonal antibodies reactive with HLA-B27. Tissue Antigens 46; 305 - 312, 1995
 
Siemoneit, K., Cardoso, M., Koerner, K., Wölpl, A., Kubanek. Human monoclonal antibodies for the immunological characterization of a highly conserved protein domain of the hepatitis C virus glycoprotein E1. Clin. Exp. Immunol. 101, 278-283, 1995

Driessen C, Hirv K, Wellinghausen N, Kirchner H, Rink L. Influence of serum on zinc, toxic shock syndrome toxin-1, and lipopolysaccharide-induced production of IFN-gamma and IL-1 beta by human mononuclear cells. J Leukoc Biol 1995;57:904-908

Driessen C, Hirv K, Kirchner H, Rink L. Divergent effects of zinc on different bacterial pathogenic agents. J Infect Dis 1995;171:486-489.

Driessen C, Hirv K, Kirchner H, Rink L. Zinc regulates cytokine induction by superantigens and lipopolysaccharide. Immunology 1995;84:272-277.

Driessen C, Hirv K, Rink L, Kirchner H. Induction of cytokines by zinc ioins in human peripheral blood mononuclear cells and separated monocytes. Lymphokine Cytokine Res 1994;13:15-20.

Siemoneit, K., Cardoso, M., Wölpl, A., Epple, S., Wintersinger, H., Koerner, K., Kubanek, K. Isotype-specific immune response to a sigle hepatits C virus core epitope defined by a human monoclonal antibody: diagnostic value and correlation to PCR. Ann Hematol, 69, 129-133, 1994
 
Wölpl, A., Fischer, M., Eiermann, Th., Goldmann, S. F. Vergleich der HLA-Typisierungs- und Retypisierungsdaten bei Patienten mit Knochenmarktransplantation. Beitr. Infusionsther. Transfusionsmed. 32; 266 - 269, 1994
 
Siemoneit, K., Cardoso, M., Wölpl, A., Koerner, K., Kubanek,.K. Isolation and epitope characterization of human monoclonal antibodies to Hepatitis C virus core antigen. Hybridoma 13, 9-13, 1994

Siemoneit, K., Wölpl, A., Wegener, S., Ernst, M., Sonneborn, H.-H., Goldmann, S. F. Generation and characterization of a human monoclonal IgG antibody specific for HLA-B12. Tissue Antigens 44; 25 - 33, 1994
 
Eiermann, Th., Ballas, M., Fakler, J., Müller, C., Wölpl, A., Goldmann, S. F. Selection of unrelated bone marrow donors: Does the current procedure warrant complete MHC class II identity? Beitr. Infusionsther. 30; 320 - 323, 1992
 
Knobloch, C., Wölpl, A., Ballas, M., Friedrich, W., Goldmann, S. F. HLA class II recognition of T cells differentiated in HLA semiallogeneic environment following bone marrow transplantation for severe combined immunodeficiency. HLA 1991, Vol. II (Editors: Tsuji, K., Aizawaam M., Sasazuki, T.), Oxford University Press, Oxford, New York, Tokyo; 449 - 451, 1992
 
Eiermann, Th., Ballas, M., Fakler, J., Wölpl, A., Goldmann, S. F. Selection of unrelated marrow donors: Does the current procedure warrant complete MHC class II identity? Infusionstherapie 19; 127 - 129, 1992
 
Ballas, M., Eiermann, Th., Wölpl, A., Goldmann, S. F. Mapping of an HLA-DRw52-associated determinant on DRb1 molecules. Tissue Antigens 36; 187 - 193, 1990
 
Goldmann, S. F., Eiermann, Th., Wölpl, A., Ballas, M. Mapping of an HLA-DRw52 associated determinant on DRb1 molecules. In: Visuals of the Clinical Histocompatibility Workshop (Editor: Terasaki, P.) One Lambda Inc., Los Angeles; 194 -195, 1990
 
Goldmann, S. F., Ballas, M., Eiermann, Th., Wölpl, A. Discrimination capacity of class II RFLP patterns in unrelated HLA-A, B, DR identical patient donor combinations. In: Visuals of the Clinical Histocompatibility Workshop (Editor: Terasaki, P.) One Lambda Inc., Los Angeles; 88 - 92, 1990
 
Eiermann, Th., Winkelmann, S., Ballas, M., Wölpl, A., Goldmann, S. F. Alloreactive T-cell clones raised in an HLA-B/D crossing over family dissect HLA-DR5 and HLA-DQw3 subtypes. Human Immunology 29; 117-130, 1990
 
Wölpl, A., Ballas, M., Eiermann, Th., Martin, R., Grosse-Wilde, H., Goldmann, S. F. DRw15 associated MLC heterozygousity confirmed by RFLP typing. In: European Histocompatibility conference, Council of Europe, Strasbourg; 190a - 190c, 1990
 
Ballas, M., Wölpl, A., Eiermann, Th., Knobloch, C., Goldmann, S. F. HLA-Class II typing by RFLP and protein chemistry reveal discrepances relevant in unrelates donor bone marrow transplantation. In: European Histocompatibility Conference, Council of Europe, Strasbourg; 86a - 86c, 1990
 
Eiermann, Th., Winkelmann, S., Ballas, M., Wölpl, A., Goldmann, S. F. Alloreactive T cell clones raised in an HLA-B/D crossing over family dissect HLA-DR5 and HLA-DQw3 subtypes. In: European Histocompatibility Conference, Council of Europe, Strasbourg; 28a - 28c, 1990
 
Ballas, M., Eiermann, Th., Wölpl, A., Goldmann, S. F. The allelic determinants HLA-DR3 and HLA-DR5 and the supertypic determinant HLA-DRw52 may be located on the same DRb chain. In: Immunbiology of HLA, Vol. II (Editor: Dupont, B.), Springer Verlag New York, 263, 1989;

Eiermann, Th., Wölpl, A., Ballas, M., Heinz, W., Arnold, R., Heit, W., Goldmann, S. F. Risk factors for GvhD and Graft Rejection in Bone Marrow Transplantation from HLA identical siblings. Bone Marrow Transplantation 4 (Suppl. 2); 116, 1989
 
Eiermann, Th., Krause, S., Wölpl, A., Ballas, M., Goldmann, S. F. Monoclonal antibody to a supertypic determinant associated with HLA-DRw52. Hybirdoma 8; 467-474, 1989
 
Steuer, M., Mauff, G., Adam, C., Baur, M. P., Bender, K., Goetz, J., Goldmann, S. F., Hauptmann, G., Neugebauer, M., Tongio, M. M., Uring-Lambert, B., Wölpl, A. An estimate on the frequency of duplicated haplotypes and silent alleles of hum C4 protein polymorphism. I. Investigation in healthy Caucasoid families. Tissue Antigens 33, 501-510, 1989

A. Wölpl, Goldmann, S. F., Eiermann, Th., Arnold, R. Die Bedeutung der Klasse III und GLO-Allele bei der Auswahl von HLA-identischen Knochenmarkspendern. In: Beiträge zur Infusionstherapie und klinische Ernährung (Hrsg.: Kretschmar, V., Stangel, W.), Karger Verlag, Basel 18; 326 - 328, 1987
 
Goldmann, S. F., Ebell, W., Blütters-Sawatzki, R., Eiermann, Th., Kreth, W., Wölpl, A., Friedrich, W. Graft versus Host Reaktion (GvHR) nach perinataler maternofetaler Transfusion bzw. nach Substitution mit Blutzellen: Der diagnostische Wert der HLA-Testung. In: Beiträge zur Infusionstherapie und klinische Ernährung (Hrsg.: Kretschmar, V., Stangel, W.), Karger Verlag, Basel 18; 321 - 325, 1987
 
Goldmann, S. F., Wölpl, A., Eiermann, Th. Erfahrungen bei der Suche eines histokompatiblen Knochenmarkspenders in der Familie und in der nichtverwandten Bevölkerung In: Beiträge zur Infusionstherapie und klinische Ernährung (Hrsg.: Kretschmar, V., Stangel, W.), Karger Verlag, Basel 18; 305 - 309, 1987

Eiermann, Th., Raghachavar, A., Wölpl, A., Ballas, M., Fischer, M., Goldmann, S. F. Generation and characterization of three new monoclonal antibodies detecting the allospecifities HLA-A2, w69, HLA-A3 and HLA-B13. Tissue Antigens 29; 201 - 207, 1987
 
A. Wölpl, Goldmann, S. F., Eiermann, Th., Arnold, R. Discrimination value of class III and glyoxalase alleles for selection of histocompatible bone marrow donors. Transplantation Proceedings 19; 2632 - 2635, 1987
 
Eiermann, Th., Martin, A., Wölpl, A., Goldmann, S. F. Evidence for a lymphocyte activation determinant coded by the HLA-region different from HLA-DR, DQ and DP. Transplantation Proceedings 19; 866 - 869, 1987
 
Wölpl, A., Lattke, H., Board, P. G., Arnold, R., Schmeiser, T., Kubanek, B., Robin-Winn, M., Pichlmayr, R., Goldmann, S. F. Coagulation factor XIII A and B subunits in bone marrow and liver transplantation. Transplantation 43; 151 - 153, 1987

Wölpl, A., Lattke, H., Arnold, R., Schmeiser, T., Kubanek, B., Robin-Winn, M., Pichlmayr, R., Goldmann, S. F. Site of synthesis of different molecules can be detected after organ transplantation. Transplantation Proceedings 18; 1343 - 1346, 1986
 
Wölpl, A., Robin-Winn, M., Pichlmayr, R., Goldmann, S. F. Fourth component of complement (C4) polymorphism in human orthotopic liver transplantation.Transplantation 40; 154 - 157, 1985
 
Northoff, H., Wölpl, A., Brewersdorf, H., Faulhaber, JD. An ABO-Blood group abnormality leading to the detection of a Colon-Carcinoma. Blut 46, 161-164, 1983
 
Wölpl, A., Goldmann, S. F. Definition of three monocyte specific antigens with human alloantisera. Transplantation Proceedings 15; 232 - 237, 1983
 

 
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